No. Carboxymethyl Cellulose Sodium N/A Nutrition & Biosciences www.pharma.dupont.com HO 00017 - 0 E L 02.2020 www.dupontnutritionandbiosciences.com . $4%&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz ? The United States Food and Drug Administration considers microcrystalline cellulose a safe material for all animal species. q9;v80 ]c\RbKSTQ C''Q6.6QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ p@" Aquacoat ECD is an aqueous dispersion of ethylcellulose used for sustained release barrier or slow release pharmaceutical coating, moisture barrier and taste masking applications for tablet and multi-particulate dosage forms. They are differentiated from each other by the amount of 3,6-anhydrogalactose as well as the number and position of ester sulfate groups present. gwf;J(e0o|1p{R~P^);ao!%{0KD7. : 160182 Date Approved: 05/25/2010 Revision No. <> This paper is based on a study of the interactions that take place during the process of hydrogel formation, break down, and recovery. 51395-75-6 Avicel RC 591. LOT #: Available upon request. This is unlikely to be a problem when Microcrystalline cellulose is consumed as part of a medical product where it is used as an excipient in the formulation. % /MediaBox [0 0 612 792] 1 0 obj GRINDSTED Xanthan Gum is a naturally fermented product of carbohydrates and is applied in various liquid, semi-solid and solid pharmaceutical dosage forms. Molecular Weight null. Production of Pharmaceutical Grade Microcrystalline Cellulose. The UK Health & Safety Executive has set workplace exposure limits at 10 mg/m3 long-term (8 hr TWA) for total inhaled dust and 4 mg/m3 for respirable dust. In the late 1960s, Avicel Microcrystalline cellulose was registered in the supplement to the National Formulary as a pharmaceutical excipient. Cellulose microcrystalline MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. EINECS #: 232-674-9 1.7. This grade of polymer film remains intact at pH< 6, thus protecting the API in gastric environments. >> Cellulose is a linear polymer of -D-glucose, linked through carbon atoms 1 and 4. <> Page 1 of 8. Delivering efficient and robust formulations. Microcrystalline cellulose was negative in the Ames mutagenicity assay [FMC Study Number I91-1189], and caused no Microcrystalline cellulose 9004-34-6 232-674-9 Not Listed * Magnesium stearate 557-04- 209-150-3 Not Listed * It is a white, free-flowing powder. Molecular weight: Not Applicable 1.5. The 'Substance identity' section is calculated from substance identification information from all ECHA databases. The main source of cellulose is woody plants, since it is the main building block of the cell walls of higher plants. PDF (28.38 mb) 2022 Corporate Fact Sheet. Protect them from sunshine or rain. The METHOCEL Premium family of water-soluble polymers for pharmaceutical applications offers exceptional flexibility and a broad range of properties typically not found in other water-soluble polymers. Microcrystalline Cellulose / Avicel PH-102. ( Avicel PH-200 microcrystalline cellulose NF, Ph. Microcrystalline Cellulose, Colloidal Silicon Dioxide: 50: 0.20 - 0.30: Best in class binder. ECOLOGICAL INFORMATION ECOTOXICITY Practically nontoxic to fish: Rainbow trout LC50 (96hr) > 100%, saturated solution (Microcrystalline cellulose, Avicel PH-101) PERSISTENCE AND BIODEGRADABILITY Inherently biodegradable. Material Safety Data Sheet or SDS for Microcrystalline cellulose 9004-34-6 from chemicalbook for download or viewing in the browser. Material Safety Data Sheet Ethyl Alcohol 70 ACC 91791 April 21st, 2019 - Material Safety Data Sheet Ethyl Alcohol 70 ACC 91791 Section 1 Chemical Product and Company Identification Ethanol has been shown to produce fetotoxicity in the embry o or fetus of laboratory animals Prenatal Chemical waste generators must determine The range of products includes three basic types of carrageenan kappa, iota and lambda from various species of red seaweed. 6 0 obj Microcrystalline cellulose is an exceptional material and one of the most widely used excipients in the pharmaceutical field. Product Name: MICROCRYSTALLINE CELLULOSE Date/ Revised: 27/November/2012 Page 1 of 4 1. The application areas for Avicel Microcrystalline cellulose are immense and encompass many industrial sectors such as food, pharmaceuticals, and cosmetics. ETHOCEL premium ethylcellulose resins are water-insoluble polymers. Gloves, eye protection and a dust mask should be used. Earth Supplied Products LLC. Revision No. This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication. It is made from purified partially depolymerised Alfa cellulose relatively free from both organic and inorganic contaminants. Interestingly, the discovery of Avicel was accidental, the team was attempting to break up hydrolysed cellulose using a Waring Blender. Terms and Conditions Compliance Solutions Industries About 3E News & Events . Product Name: Microcrystalline Cellulose E460 1.2. Enter your [postal] code to see information about local products, representatives and retailers, along with special offers in your area. cas:9000-11-7 msds Carboxymethyl cellulose. Dupont acquired the microcrystalline cellulose business of FMC Corporation in 2017. MATERIAL SAFETY DATA SHEET Avicel PH Microcrystalline Cellulose MSDS Ref. Microcrystalline cellulose (MCC) is one of the most important tableting excipients thanks to its outstanding dry binding properties, enabling the manufacture of tablets by direct compression (DC). All Rights Reserved. It is highly versatile and is therefore also widely used in topicals and semi-solid & liquid dosage forms, including ointments, creams, gels, pastes, solutions, suspensions, and emulsions. if interested in purchasing or obtaining a sample for assessment, you should contact Dupont themselves directly. Avicel Microcrystalline cellulose is a type of cellulose, a naturally-occurring, large molecular weight polysaccharide found in woody plants. Similarly, the European Food Safety Agency has also evaluated Microcrystalline cellulose and established that it is not absorbed systemically and excreted unchanged. <> DC remains the most economical technique to produce large batches of tablets, however its efficacy is directly impacted by the raw material attributes. )rFHVNzNaJlIo$5ZH(`8Z>s'$UVVWUyD+[t? 1 0 obj Avicel CL-611 Microcrystalline Cellulose and Sodium Carboxymethylcellulose Manufacturer FMC Corporation Product code 103-B Revision date 2014 September 30 Language English. <> ( More than 65 years later, Avicel continues to command global acceptance, with no signs of its popularity waning. stream 86dXeaAjHe%d*`&>>&_p}=X|_% fTtC aB s!YaxHWtGr"GQ 5S"fMS+_;x@@5 zjrK=;OA:il)b> e ei'wm~oh!=Z@Y:J0#8On`T./iC}^o%7KS"$ rf*Z;JTL-uOHH%%Z,029J_ ( endstream endobj 526 0 obj 465 endobj 527 0 obj << /Filter /FlateDecode /Length 526 0 R >> stream Generally, these can be classified into two broad groups: Standard grades, and Co-processed grades. Avicel RC-591 & CL-611 - Description. Non-woody sources are also viable sources of cellulose, although only woody plants and cotton are the main sources for microcrystalline cellulose used as a pharmaceutical excipient. To meet their exacting standards, we deliver a wide choice of relevant solutions that are simultaneously replicable, scalable and high performing. /Contents 4 0 R Performing this action will revert the following features to their default settings: Hooray! Powder becomes slippery when wet. Their nomenclature and recommended applications are shown below: Co-processed Avicel grades are high functionality materials designed to bring added performance over and above what standard grades offer. MATERIAL SAFETY DATA SHEET Version: 1.0 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Material Name: Estradiol Tablets Trade Name: RONFASE . pH 6.0 to 8.0 . However, it yields non-digestible fibre. Frijlink, Compaction mechanism and tablet strength of unlubricated and lubricated (silicified) Microcrystalline Cellulose, European journal of Pharmaceutics and Biopharmaceutics, 59 (2005) 133-138. PDF (4.11 mb) Footer menu 1. Find answers in our support articles. 5 0 obj Chemical Formula: (C6H10O5)n 1.4. Avicel RC-591 offers ideal thixotropic bahavior for stabilizing suspensions while Avicel CL-611 is a stabilizer for reconstitutable or dry suspension formulations. gac74 [#B6`Wnw7 It is also used in plaque assays for counting. Eur., JP Product Specifications: Chemical and Physical: Loss on drying 2.0 - 5.0 %* Bulk density 0.29 - 0.36 g/cc Identification A, B Passes Degree of polymerization NMT 350 units pH 5.5 - 7.0* Conductivity NMT 75 S/cm Apply today! Thus, Avicel contributes no or very few calories to the food system. 4 0 obj II: effects of changes in the content of Microcrystalline Cellulose, AAPS PharmSci, 2 (2000) 45. The fumarate moiety of Alubra increases its melting temperature, which allows for greater functionality at high press speeds while the stearate chain maintains the lubricity of the compound and supports low ejection forces. An internally cross-linked sodium carboxymethyl cellulose (NaCMC), it aids in the disintegration and drug dissolution of pharmaceutical tablets, capsules, and granules. /Producer(Sub Systems, Inc.)/CreationDate(D:20181207095625+05'00')/ModDate(D:20181207095625+05'00')/Creator(Sub Systems, Inc.) The data shown below apply only to Avicel PH 101. %PDF-1.4 Explore how we work and why we apply science and creativity for a better world to everything we do. Cellulose microcrystalline Revision Date 25-Dec-2021 SARA 313 Not applicable SARA 311/312 Hazard CategoriesSee section 2 for more information CWA (Clean Water Act) Not applicable Clean Air Act Not applicable OSHA - Occupational Safety and Health Administration Not applicable CERCLA Not applicable California Proposition 65 This product contains the following Proposition 65 chemicals. A., and Smith, P. A. They are made up of sulfated and non-sulfated repeating units of galactose and 3,6-anhydrogalactose. /Type/Page Avicel Microcrystalline cellulose is manufactured in the United States of America by Dupont. CAS #: 9004-34-6 1.6. Assay: 0.98 Appearance: Off white to slight yellow solid Package: 1L 5L 10L 25L bottle Storage: Stored in shaded, cool and dry places Transportation: Handle with cares to avoid damaging the packages. ChemicalBook. All rights reserved. Material Safety Data Sheet or SDS for Cellulose microcrystalline 102331 from Merck for download or viewing in the browser. J]3yzZ2Z$mZ7o%-Xyq'()V9KX0gk~AA Cu:3(]N"AQdUt~h|P Microcrystalline Cellulose; Cellulose; Functions. The representative usage of Avicel PH-101 and Avicel PH-102 Microcrystalline cellulose in wet granulation and direct compression is shown in the following two examples. %PDF-1.5 XiDqLN MD'F2`jI7ZWu,JK%5e9~:R>LAm\WyY0lk=ZNP;pZ23)P0GG~%e[ d8GIXRo&. q9;v80q>jZ Synergies to simplify formulation challenges and reduce operational costs. Microcrystalline Cellulose Side Effects. microcrystalline cellulose and carboxymethylcellulose sodium NF, Ph. The charts below provide guidance on how to select and use standard and co-processed grades of Avicel Microcrystalline cellulose in pharmaceutical products. <> . A family of polysaccharide products that allow distinctive drug delivery solutions. Avicel CL-611 Microcrystalline Cellulose and Sodium Carboxymethylcellulose Page 1 of 9. !(!0*21/*.-4;K@48G9-.BYBGNPTUT3? JRS Pharma: PROSOLV SMCC 90 LM: Microcrystalline Cellulose, Colloidal Silicon . vdZ@Rgl{eU+7N!3!|hUmW)~}U*7k i@j)q["MEydtP"ftFu]t }JN~A"8lz7#}J.i@ qaj/QU<5OrVMfl{pL? Microcrystalline cellulose has excellent compressibility properties and is widely used in solid forms such as tablets that are hard, but can dissolve quickly, and this has increased its demand in . (AEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEM %)piQpFNnFu\4m4( ESE;m& %QL((((((((((((((((((((((((((((((((((((((((P3NhC The formed cellulose molecules pack themselves closely to each other, stabilised through hydrogen bonds, creating crystalline regions interspersed with amorphous regions. Low use levels of GRINDSTED Xanthan Gum are sufficient to provide desired viscosities and textures. ?t#_n|z%4n#(!:lMD~{mfvv}Na0vx?? Alubra sodium stearyl fumarate from IFF Pharma Solutions is a comparatively hydrophilic lubricant widely used in capsule and tablet formulations. 9,LL!z The aqueous solution to barrier membrane coating. 3t;zAXa[j.7ZX[GL9e,>6sVV`T6`#W 2021 Annual Report. Interestingly, the discovery of Avicel was accidental, the team was attempting to break up hydrolysed cellulose . MATERIAL SAFETY DATA SHEET. Created Date: 2/10/2020 8:51:41 PM . Our customers around the world enjoy the benefits of TEXTURECEL NaCMC in various wound care products, too. Accumulation of overhead settled dust may form explosive concentrations in air when disturbed and dispersed. FMC BioPolymer 1735 Market Street Philadelphia, PA 19103 (800) 526-3649 . A schematic illustration of the manufacturing process for Avicel Microcrystalline cellulose is shown below. HMo@9, U Q!R/1*;` ;(Imu9Jv_ YhnHTbwP*:mg"T{BO;!QR e,cqO! zW0} kAmS AYiy QJVWwi ED`52u-I~_ViT3+3kIT D2/A5vP5MHt(*vCBZ5UALFS0Mr v6t3dDda!03O$V>S6n| 3Fz. Revision No. stream The product range encompasses methylcellulose and hydroxypropyl methylcellulose (hypromellose) each available in different grades to address a wide range of applications including tablet coatings, granulation, controlled release, drug layering, vegetarian hard-shell capsules and amorphous drug stabilization. Learn about FMC's differentiated biologically-based crop solutions. The smallest units, the elementary fibrils (cellulose crystalline strands) are made up of many -(1-4) glucose chains which are bundled to form microfibrils. G2W4de=u183KGH{ vQ#4:1\wc << <> Pharmacel 112 is a directly compressible microcrystalline cellulose grade with a low moisture content (LOD Max. LATTICE Microcrystalline Cellulose has many important uses within the food, pharma, specialty applications and industrial such . SUBSTANCE IDENTIFICATION 1.1. bEI3%UxI"M_1)5b/c;/\~3:?/9S\\9/%I3nn2foO^MgX0n: O Chemical Formula: (C6H10O5)n 1.4. endobj Explore how you can develop your career and bring your creative ideas to life at IFF. CoA. Ac-Di-Sol Croscarmellose Sodium is one of our flagship offerings for pharmaceutical manufacturers. Van Veen, G.K. Bolhuis, Y.S. Wu, K. Zuurman, H.W. The typical mean particle size is 20200 m. Microcrystalline Cellulose. Copyright 2023 by International Flavors & Fragrances Inc. IFF is a Registered Trademark. Avicel Microcrystalline Cellulose: A Guide to Grades and Uses, Working Hours (Mon to Friday): 08:30 - 17:30, legendary Canadian-born chemist, Orlando Aloysius Battista, United States Pharmacopoeia and National Formulary, United States Food and Drug Administration, Quantitative nutritional analysis of Avicel Microcrystalline cellulose (in 100g), https://doi.org/10.1016/0378-5173(95)04231-8, https://doi.org/10.1016/j.ejpb.2004.05.009, https://doi.org/10.1002/9783527682935.ch04, Pharmaceutical Acronyms and Abbreviations, Glossary of Terms Used in the Pharmaceutical Industry, Standard Terms & Conditions Of Sale Of Goods And Services, 4-O-[(1S)-hexopyranosyl]-D-glycero-hexopyranose. Avicel PC 611 (FMC Biopolymer) Supplied by. 0.25 - 0.37. Biologicals by FMC. endobj It can be processed both via wet granulation and direct compression, as well as roller compression and extrusion-spheronisation. /Parent 3 0 R Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents. Trademarks: Avicel PH-102. In summary, Avicel microcrystalline cellulose is virtually inert, its energy content is very low or zero and it is not absorbed. Product and Company Identification Product Name Microcrystalline Cellulose CAS Number 9004-34-6 Parchem - fine & specialty chemicals 415 Huguenot Street New Rochelle, NY 10801 (914) 654-6800 (914) 654-6899 parchem.com info@parchem.com EMERGENCY RESPONSE NUMBER The table below lists the typical nutritional information of microcrystalline cellulose: Quantitative nutritional analysis of Avicel Microcrystalline cellulose (in 100g)1. As one of the most robust and efficient excipients, it tolerates high salt content, high temperature and is stable in a wide pH range. Alginate drug delivery harnesses the unique properties of seaweed for premier performance in multiple pharmaceutical and nutraceutical applications; they impart viscosity in solutions and even form a three-dimensional gel in the presence of calcium ions. endobj Instead, they obtained a stable colloidal suspension. Explore our end markets, products, ingredients and essential solutions or get in touch with us about your order. Test Data Available. Avicel PC 611 (FMC Biopolymer) . Browse Avicel PH-101 and related products at MilliporeSigma. Go to Investor Relations. Alubra is also less susceptible to over-blending contributing to more flexible process conditions and reduced waste due to over blended batch failures. stream >> 10.1 Future Forecast of the Global Microcrystalline Cellulose Market from 2023-2028 Segment by Region 10.2 Global Microcrystalline Cellulose Production and Growth Rate Forecast by Type (2023-2028 . Of all the different brands and grades of MCC, Avicel PH 101 or Emcocel 50 has been the most widely used. : 5 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication Standard, 29 CFR 1910.1200 and Canadas Workplace Hazardous Materials Information System (WHMIS) requirements. CAS No. Within the pharmaceuticals field, where the bulk of this material is utilised, Avicel Microcrystalline cellulose functions as a filler and diluent, dry binder, flow, disintegrating, and compression aid in tablets, capsules, and granules. Various Gelcarin and Viscarin carrageenan grades are used by the pharmaceutical industry to achieve specific gelling for controlled drug release, thickening, and stabilizing properties desired in various formulations. Standard, 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS . In roller compaction, Avicel Microcrystalline cellulose improves compaction during the ribbon phase, enabling a trouble-free process while also preserving the plasticity of the compacts. Fmc Corporation: Ultra-fine microcrystalline cellulose compositions and process . Are you sure you want to delete your template? : 9 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication . The global Microcrystalline Cellulose (Mcc) market size is projected to reach multi million by 2026, in comparison to 2022, at unexpected CAGR during 2022-2026. Millipore. In Cellulose and Cellulose Derivatives in the Food Industry, T. Wstenberg (Ed. Hi, let us know if you have any questions as you visit our website. In many applications, one METHOCEL product can perform the job of two, three or even more ingredients saving money and time. Although the breakup of cellulose to form colloidal microcrystalline cellulose has no impact on calorific content of the material, colloidal microcrystalline cellulose contain soluble components (hydrocolloids) that are introduced during processing, which add calories to the product. They are soluble in a wide range of organic solvents, beginning with aliphatic alcohols such as ethanol and isopropanol, and are compatible with most other familiar organic solvent chemistries, including ether alcohols, ketones, aromatic hydrocarbons and many more. FMC Corporation: Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations DE102009022738A1 (de) * 2009-05-26: 2010-12-09: J. Rettenmaier & Shne Gmbh + Co. Kg . 4 0 obj When selected in wet granulation, the optimum level of use is between 5 and 20%, although higher levels have been successfully used. CAS 9004-34-6. Doses up to 30 g per day appear to be . F. Steele, M. Tobyn, S. Edge, A. Chen & J. N. Staniforth.Physicochemical and Mechanical Evaluation of a Novel High Density Grade of Silicified Microcrystalline Cellulose, Drug Development and Industrial Pharmacy, 30:1 (2004), 103-109. This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication ]2}Sb2Wdn-;^}n(/;r\'l3--l~ kuI?H>$7;!l|g|i4&dtb/O3!C!#\qpg+>Q0OM Patel, F. Podczeck, Investigation of the effect of type and source of Microcrystalline Cellulose on capsule filling, International Journal of Pharmaceutics, 128 (1996) 123-127. <> l~5C : 5. We know that our customers need to provide reliable and consistent products to their patients. The table below lists the most important chemical identifiers applicable to Avicel Microcrystalline cellulose. Meet our leadership team. Formulators select it when they need to enhance a formulations robustness especially when less compactable diluents and binders are used. FMC has deep roots in the food production system worldwide learn more about our latest advances in the future of agriculture. Microcrystalline cellulose is a term for refined wood pulp and is used as a texturizer, an anti-caking agent, a fat substitute, an emulsifier, an extender, and a bulking agent in food production. Note that Avicel Microcrystalline cellulose is available in different particle sizes and moisture grades that have different properties and applications. By producing Avicel . [FMC Study Number I92-1464]. 0.25 - 0.37. Cellulose microcrystalline. Aquacoat CPD is an aqueous dispersion of cellulose acetate phthalate used for enteric release applications. It . X`I%&/m{JJt`$@iG#)*eVe]f@{{;N'?\fdlJ!?~|? It flows and compresses extremely well, properties that endear this material wide scope of use in many fields. The figure below illustrates the structural organisation of cellulose within plants. Upon ingestion, microcrystalline cellulose is not absorbed into the blood stream and therefore has little toxicological potential. METHOCEL products have been in continuous production for more than 70 years with production facilities and deep product expertise located around the globe. FMC Corporation 2929 Walnut Street Philadelphia, PA 19104 (215) 299-6000 (General Information) . Product Name: Microcrystalline Cellulose 1.2. Currently, it is marketed both directly and indirectly (through distributors) depending on the country in question. }o]X4]. 1.5% w/w), especially designed for formulating active pharmaceutical ingredients (APIs) with a high sensitivity for moisture. The table below shows the most common physicochemical parameters of this raw material. endobj Your file is uploaded and ready to be published. Document(s): certificate data msds. The MCC can be synthesized by different processes such as reactive extrusion, enzyme mediated, steam explosion, and acid hydrolysis. They are high molecular weight, highly sulfated, linear molecules with a galactose backbone. /PRNewswire/ -- ReportsnReports added Global Microcrystalline Cellulose (MCC) Market Growth 2019-2024 to its online research database. endobj Avicel is a brand name by Dupont for grades of Microcrystalline cellulose. Description: Microcrystalline Cellulose is a term for refined wood pulp manufactured through plant fibre hydrolysis. lH5JWy}DgKRR"Fs w !1AQaq"2B #3Rbr Looking for FMC'searnings news? SUBSTANCE IDENTIFICATION 1.1. These grades have particle sizes ranging from <30 to approximately 200. If you are already a ChemPoint customer then sign up for access to our online ordering website. If you have Crohn's disease or a history of bowel obstruction, discuss with a doctor or pharmacist about drug interactions with fiber supplements.. Microcrystalline Cellulose E460 MSDS 1. You have already flagged this document.Thank you, for helping us keep this platform clean.The editors will have a look at it as soon as possible. LATTICE Microcrystalline Cellulose has many important uses within the food, pharma, specialty applications and industrial such as non-stick coatings, insulation of wiring, crop protection and paints,coats and inks. pfTr^i5wOg)y .6 68ZWN hZB{u7ps@uWm 2#@+o/Z {vd^qHe42)Xz[T|[6:q/ i0lGX*}L[7;SGS "lj@::4G[IN{ EMCOCEL XLM 90. Product and Company Identification . 1. MATERIAL SAFETY DATA SHEET Avicel PC 611 Microcrystalline Cellulose Page 1 of 8 MSDS Ref. IFF has decades of experience controlling these naturally derived materials, which means you can count on consistent performance, every time. Studies from the World Health Organisation and the European Food Safety Agency have concluded that Microcrystalline cellulose has no safety concerns for the public when used in animal nutrition. Medium size standard MCC grade, suited for the majority of directly compressible actives. Microcrystalline cellulose in certain fiber supplements may cause mild side effects ().These may include gas, bloating and increased stool production..
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