Cassano, N., Mantegazza, R., Battaglini, S., Apruzzi, D., Loconsole, F., and Vena, G. A. Exp Clin Endocrinol Diabetes 2003;111:341-3. Corse, F. M., Galgani, S., Gasparini, C., Giacanelli, M., and Piazza, G. Acute hypokalemic myopathy due to chronic licorice ingestion: report of a case. J Ethnopharmacol. Harada M, Suzuki M, Ozaki Y. Feng Z, Xu J, He G, et al. A., van der Ven, P. F., Martin, M., Sherman, J., and Haley, J. Nutr Res 2012;32(2):85-92. Jia, Y. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. View abstract. Aliment Pharmacol Ther 2004;20:1279-87. Awad N, Makar G, Burroughs V, Ravi P, Burroughs SR. Licorice-induced apparent mineralocorticoid excess causing persistent hypertension and hypokalemia. View abstract. View abstract. Complement Ther Clin Pract. Zong, P. P., Yan, T. Y., and Gong, M. M. [Clinical and experimental studies of effects of huayu decoction on scavenging free radicals]. Zhong.Xi.Yi.Jie.He.Za Zhi. Fugh-Berman, A. Herb-drug interactions. View abstract. Planta Med 1991;57(2):119-121. Am J Chin Med 1992;20(3-4):313-317. 1986;6(12):714-6, 707. Shen, A. Y., Wang, T. S., Huang, M. H., Liao, C. H., Chen, S. J., and Lin, C. C. Antioxidant and antiplatelet effects of dang-gui-shao-yao-san on human blood cells. Tu, J. H., He, Y. J., Chen, Y., Fan, L., Zhang, W., Tan, Z. R., Huang, Y. F., Guo, D., Hu, D. L., Wang, D., and Hong-Hao Zhou. Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. Feng ZT, Xu J, He GC, Cai SJ, Li J, Mei ZG. About Dr.Cope. View abstract. Chin, Y. W., Jung, H. A., Liu, Y., Su, B. N., Castoro, J. Int Immunopharmacol. View abstract. Select a condition to view a list of vitamins. Other conditions. A multicentre trial. Asia Pac.J Clin Nutr 2008;17(1):17-22. Hossain, M. S., Takimoto, H., Hamano, S., Yoshida, H., Ninomiya, T., Minamishima, Y., Kimura, G., and Nomoto, K. Protective effects of hochu-ekki-to, a Chinese traditional herbal medicine against murine cytomegalovirus infection. . View abstract. The author has contributed to research in topic(s): Rheum officinale. Chinese herbal medicine for atopic eczema. Koo YK, Kim JM, Koo JY, et al. [Protective mechanism of Salvia miltiorrhiza and Paeonia lactiflora for experimental liver damage]. The sweet cake that reaches parts other cakes can't! The glycyrrhizin and glycyrrhetic acid constituents of licorice have significant anti-androgen effects, 32-34 which may be helpful in reducing androgenic symptoms in women with PCOS. Practitioner 1973;210:820-3. Drug Metab Dispos 2002;30:709-15.. View abstract. [Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis]. Hataya Y, Oba A, Yamashita T, Komatsu Y. Hyponatremia in an elderly patient due to isolated hypoaldosteronism occurring after licorice withdrawal. View abstract. Licorice is an herb that grows in parts of Europe and Asia. To learn more about how herbs are used to treat infertility, see this article. Nephron 2002;90:240. Life Sci 1993;53(5):PL63-8. View abstract. View abstract. American Herbal Products Association's Botanical Safety Handbook, Second Edition. Health Care Women Int. View abstract. Nippon Rinsho 1994;52:1817-22. Med Princ Pract 2010;19(6):485-489. N Engl J Med 1990;322:850. Br J Clin Pract 1972;26(12):563-566. Licorice-induced hypermineralocorticoidism. Eur J Pharmacol 1981;72:219-25.. View abstract. Review of over-the-counter treatments for aphthous ulceration and results from use of a dissolving oral patch containing glycyrrhiza complex herbal extract. Fung AY, Look PC, Chong LY, et al. Low potassium levels can increase the side effects of digoxin. Helpful. A dual investigation of the effect of dietary supplementation with licorice flavonoid oil on anthropometric and biochemical markers or health and adiposity. Am J Med Sci 2003;325:153-6. 1979;14(5):605-607. View abstract. Abe Y, Ueda T, Kato T, Kohli Y. Peony and Licorice is a safe and gentle yet powerful formula that is famous for its ability to build blood and balance menstrual cycles. In my research, I found that like with any natural. White peony ( bai shao in Chinese) is root without any bark, while red peony . Nihon Jinzo Gakkai Shi 2010;52(1):80-85. 2020 Dec;58(1):352-356. BMJ 1997;314:731-2. Cancer 1997;79(8):1494-1500. J Clin Endocrinol Metab 2003;88:2384-92. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. Chinese peony root comes in two different forms. Some research suggests that licorice extract may help kill bacteria in the mouth that cause tooth decay. View abstract. Part 182 -- Substances Generally Recognized As Safe. Am J Chin Med 1996;24:165-8. The yellow-brown thick-branched roots are used as medicine. Nutrition 2002;18(3):268-273. J Cosmet.Sci 2006;57(1):57-64. Therapeutic basis of glycyrrhizin on chronic hepatitis B. Antiviral Res 1996;30:171-7. View abstract. View abstract. Z., Zhang, Y. Hypokalaemia and hypertension associated with use of liquorice flavoured chewing gum. BMJ Case Rep 2012;2012. Chewing tobacco flavored with Licorice may cause serious side effects such as high blood pressure. Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. View abstract. de Klerk GJ, Nieuwenhuis G, Beutler JJ. Lee, C. H., Park, S. W., Kim, Y. S., Kang, S. S., Kim, J. PCOS; Fertility; 25 - 45; Menopause; 45 - 60; Pregnancy Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: Aspirin; Clopidogrel; Warfarin; St. John's wort. View abstract. View abstract. View abstract. View abstract. O'Connell K, Kinsella J, McMahon C, Holian J, O'Riordan S. Posterior reversible encephalopathy syndrome (PRES) associated with liquorice consumption. Digestion 2004;69:45-52. Glycyrrhizin-Induced Pseudohyperaldosteronism: A Case Report. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. Because licorice has a hormone-like effect, it can relieve excessive gastric acid secretion. View abstract. View abstract. View abstract. Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. View abstract. View abstract. Previous studies have estimated that a dose of 1 to 5 grams (g) of licorice root daily is safe for most adults. Hajiaghamohammadi, A. In an ovarietctomized model, oral administration of a combination of white peony and licorice increased DHEA and serum estrogen concentration. View abstract. View abstract. Gut 1969;10:299-302. View abstract. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. Korri, H., Awada, A., Baajour, W., Beaini, M., and Nasreddine, W. [Rapidly progressing quadriparesis secondary to licorice (souss) intoxication]. Lancet 2000;355(9198):134-138. Wang W, Tian DD, Zheng B, et al. View abstract. Effects of the Japanese herbal medicine "Sho-saiko-to" (TJ-9) on in vitro interleukin-10 production by peripheral blood mononuclear cells of patients with chronic hepatitis C. Hepatology 1997;25(6):1390-1397. J Endocrinol Invest 1990;13(10):847-848. Lee, I. T., Lee, W. J., Tsai, C. M., Su, I. J., Yen, H. T., and Sheu, W. H. Combined extractives of red yeast rice, bitter gourd, chlorella, soy protein, and licorice improve total cholesterol, low-density lipoprotein cholesterol, and triglyceride in subjects with metabolic syndrome. View abstract. Loop diuretics can also decrease potassium levels. Phytother.Res. Acharya SK, Dasarathy S, Tandon A, et al. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Mattarello MJ, Karbowiak I, Ermolao A, and et al. View abstract. Efficacy and tolerability of hydroalcoholic extract of Paeonia officinalis in children with intractable epilepsy: An open-label pilot study. A Rutgers expert discusses how eating black licorice can affect your health. View abstract. Blood Press. 2007;30(7):1271-7. View abstract. View abstract. Ann Pharmacother 2003;37(6):836-838. Hypertension encephalopathy after liquorice ingestion. Nephol Dial Transplant 1999;14:218-20. Steroids 2005;70(8):538-542. View abstract. View abstract. After lab testing, the Cheng team found that Huang Qin Tang had a high inhibitory property against the debilitating side effects of a chemotherapy drug called CPT-11 (later approved as irinotecan), including diarrhea, nausea, and vomiting. Ann Clin Biochem 2007;44(Pt 4):397-399. Peters, M. C., Tallman, J. Effect of glycyrrhizin on the activity of CYP3A enzyme in humans. View abstract. Br J Dermatol 1992;126:179-84. J Clin Periodontol 1991;18(3):210-212. View abstract. View abstract. View abstract. 2019;33(1):117-29. Clin Ter 1990;132(1):55-58. Chien, C. F., Wu, Y. T., and Tsai, T. H. Biological analysis of herbal medicines used for the treatment of liver diseases. Z., Zhang, Y. Contact Dermatitis 1999;40(1):56. "It contains liquiritin, an active compound that helps to disperse and remove existing melanin in the skin," explains Chwalek. Sakamoto S, Kudo H, Suzuki S, et al. Eur J Obstet Gynecol.Reprod Biol 2007;131(1):61-67. J Gastroenterol 1996;31(5):691-695. Hattori, T., Ikematsu, S., Koito, A., Matsushita, S., Maeda, Y., Hada, M., Fujimaki, M., and Takatsuki, K. Preliminary evidence for inhibitory effect of glycyrrhizin on HIV replication in patients with AIDS. Fitoterapia 2004;75:45-9.. View abstract. Baba, M. and Shigeta, S. Antiviral activity of glycyrrhizin against varicella-zoster virus in vitro. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. View abstract. [Application of dannang recipe no. Ai, M., Yamaguchi, T., Odaka, T., Mitsuhashi, K., Shishido, T., Yan, J., Seza, A., and Saisho, H. Objective assessment of the antispasmodic effect of shakuyaku-kanzo-to (TJ-68), a Chinese herbal medicine, on the colonic wall by direct spraying during colonoscopy. The herb licorice may lower warfarin levels and can add to digoxin's effects. Int J Cardiol 2008;124(3):e42-e44. MacKenzie, M. A., Hoefnagels, W. H., Jansen, R. W., Benraad, T. J., and Kloppenborg, P. W. The influence of glycyrrhetinic acid on plasma cortisol and cortisone in healthy young volunteers. van Uum SH. [Clinical study on effect of recombinant roasted licorice decoction combined with low-dose glucocorticoids in treating idiopathic thrombocytopenic purpura]. Yoon JY, Cha JM, Hong SS, et al. Chamberlain, J. J. and Abolnik, I. View abstract. Treatment of duodenal ulcer with glycyrrhizinic-acid-reduced liquorice. Clin Neurol Neurosurg 1993;95(1):35-37. Johns, C. Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars. Gupta D, Agrawal S, Sharma JP. View abstract. J Ethnopharmacol 2004;94:339-44. . Phytother Res 2008;22:563-5. View abstract. Sheth, V. M. and Pandya, A. G. Melasma: a comprehensive update: part II. View abstract. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . Jin, C. Y., Wang, D. L., and Fang, Z. D. [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. A controlled trial of a dissolving oral patch concerning glycyrrhiza (licorice) herbal extract for the treatment of aphthous ulcers. Anesth Analg 2009;109(1):77-81. Biofactors 2009;35(1):98-104. View abstract. Attou R, Redant S, Honore PM, Preseau T, Hantson P, De Bels D. Liquorice intoxication can lead to cardiac arrest! Luchon, L., Meyrier, A., and Paillard, F. [Hypokalemia without arterial hypertension by licorice poisoning]. Brayley J, Jones J. Life-threatening hypokalemia associated with excessive licorice ingestion (letter). Therapeutic Research Faculty 2020. A., van Dokkum, W., and Savelkoul, T. J. Glycyrrhizic acid: the assessment of a no effect level. View abstract. Dong quai grows at high altitudes in the cold, damp, mountains of China, Korea, and Japan. Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora. Overview. Eagon PK, Elm MS, Hunter DS, et al. Diane Calello, executive medical director of the New Jersey Poison Control Center, based at Rutgers New Jersey Medical School, discusses safe . Nishioka, K. and Seguchi, T. Contact allergy due to oil-soluble licorice extracts in cosmetic products. View abstract. Kormann R, Languille E, Amiot HM, Hertig A. Licorice, tobacco chewing, and hypertension. The effect of dong quai on menopausal symptoms is unknown. View abstract. Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. View abstract. Paeoniflorin, a constituent of white peony root, has demonstrated inhibition of testosterone synthesis in vitro, without affecting estradiol synthesis.It reduces testosterone production by the ovaries but not the adrenal glands. Licorice that has had this substance removed (called DGL for deglycyrrhizinated licorice) may not have the same degree of side effects. Exp Med Surg 1969;27:411-20. Evid Based Complement Alternat Med 2016;2016:9852793. This information may not fit your specific health circumstances. Licorice can decrease how quickly the body breaks down corticosteroids. OTHER NAME(S): Acide Glycyrrhizique, Acide Glycyrrhizinique, Alca. Akbari N, Asadimehr N, Kiani Z. Tacconi, P., Paribello, A., Cannas, A., and Marrosu, M. G. Carpal tunnel syndrome triggered by excessive licorice consumption. Life Sci 2-23-2001;68(14):1687-1694. Ruiz-Granados, E. S., Shouls, G., Sainsbury, C., and Antonios, T. A salty cause of severe hypertension. The biological compound pesticide is manufactured from the raw materials of Ailanthus altissima Swingle, Cyrtomium fortunei, geranium wilfordii, fructus forsythiae, Scutellaria baicalensis, gallnut, areca-nut, coconut shell, radix sophorae . Mol Cell Endocrinol. View abstract. View abstract. The benefits of licorice root can be enjoyed as a tea, supplement, tincture, or topical treatment, and even as candies. Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. 2005;25(6):540-542. Proanthocyanidins, flavonoids, tannins, polysaccharides, and paeoniflorin are all considered to contribute to the medicinal activity of various forms of peony. It is used for stomach pain, abdominal pain and acute pain of gastrocnemius muscle contracture, etc. View abstract. Yasue H, Itoh T, Mizuno Y, Harada E. Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. Am J Clin Dermatol 2010;11(4):247-267. Chen, W. G. and Ba, Z. M. Prof. ZHANG Yi's experience in treating severe arrhythmia. Dai DW, Singh I, Hershman JM. Antiviral Res 2003;59(1):41-47. ['Licorice hypertension' also caused by licorice tea]. View abstract. Little is known about whether it's safe to use licorice root while breastfeeding. View abstract. Ann Noninvasive Electrocardiol. J Assoc Physicians India 1989;37(10):647. J Clin Psychopharmacol 2008;28(3):264-370. View abstract. Liquorice and hypertension. J Ethnopharmacol 2011;135(1):162-72. Although white peony is generally considered safe for most people, drinking large amounts might have some negative consequences. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. October 15, 2021. Effect of glycyrrhizin-containing toothpaste on dental plaque reduction and gingival health in humans. Man SC, Li XB, Wang HH, et al. View abstract. View abstract. View abstract. 5-10-2004;208(1):89-94. Scali, M., Pratesi, C., Zennaro, M. C., Zampollo, V., and Armanini, D. Pseudohyperaldosteronism from liquorice-containing laxatives. Hum Exp Toxicol 2012;31(12):1295-1298. [The nature of an anticoagulant isolated from peonies in the central zone of Russia]. [Peony tincture in the complex treatment of allergic dermatoses]. Int J Nurs Stud 2016;63:9-17. View abstract. Evid Based Complement Alternat Med 2016;2016:8292486. Ruetzler K, Fleck M, Nabecker S, Pinter K, Landskron G, Lassnigg A, You J, Sessler DI. View abstract. View abstract. Cisplatin is used to treat cancer. Am J Nephrol 2000;20:145-8. View abstract. View abstract. Ital J Neurol Sci 1983;4(4):493-497. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. Licorice might increase blood pressure. Int J Dermatol 1999;38:387-92 . 2010 Nov;35(10):1587-93. View abstract. View abstract. Messier, C., Epifano, F., Genovese, S., and Grenier, D. Licorice and its potential beneficial effects in common oro-dental diseases. Am.J Chin Med 2004;32(4):569-578. Effect of licorice on reduction of body fat mass in healthy subjects. May Harm Baby During Pregnancy. Side effects, toxicity, and interactions. View abstract. View abstract. Lee, C. K., Park, K. K., Lim, S. S., Park, J. H., and Chung, W. Y.
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